* Killer whales: Killer whales are also known to prey on spotted eagle rays. Killer whales are large, powerful predators that hunt in pods and can take down even large prey.
* Dolphins: Some dolphin species, such as the bottlenose dolphin and the Risso's dolphin, have been known to prey on spotted eagle rays. Dolphins are intelligent predators that use their teamwork and echolocation to hunt for prey.
* Sea lions: Sea lions, such as the California sea lion and the Steller sea lion, have also been known to prey on spotted eagle rays. Sea lions are powerful predators that use their speed and agility to catch their prey.
* Humans: Humans are also a major predator of spotted eagle rays. Spotted eagle rays are often caught for their meat, fins, and skin.