Side Effects of Prednisone in a Feline

Prednisone is a glucocorticoid, which means that it is related to cortisone and contains glucose. When given to a cat, it is intended to reduce swelling, pain and redness. According to Wedgewood Pharmacy, cats may require higher doses of prednisone than dogs, but they are not as prone to negative side effects.
  1. Excessive Thirst

    • A cat that is being given prednisone may exhibit excessive thirst. Because prednisone elevates kidney activity, it leads to the conservation of salt in the body. The excessive thirst can cause excessive urination as well. The solution for this side effect is to switch out medications or to cut back on the dose of prednisone.

    Excessive Appetite

    • Prednisone can also cause excessive appetite in cats. This may mean that they are constantly begging for treats or they finish their own food very quickly and start looking for more. This can result in quick weight gain. Quick weight gain is a symptom that should be discussed with your veterinarian to make sure that it isn't due to another issue, but it is a common side effect of prednisone.

    Stomach Problems

    • At higher dosages of prednisone, a cat may begin to experience stomach issues. The cat's gastrointestinal tract may become irritated, which leads to discomfort and, in some cases, diarrhea. The cat may respond with listlessness and lethargy, and it may seem to spend a large amount of time in the litter box. If a cat has stomach problems due to prednisone, another medication should be used instead.

    Behavioral Changes

    • Prednisone can cause behavioral changes in some cats. A cat that was friendly and outgoing may become shy and reserved, while a cat that was always even-tempered may become less patient. If these behavioral changes are ongoing and disruptive, speak with the veterinarian, as a different medication may be required, or a psychological medication can be introduced.