Side Effects of Clindamycin Drops in a Cat

Clindamycin is an antibiotic in the lincosamide class, given orally to dogs and cats to combat oral infections, abscesses, bone infections and deep wounds. Clindamycin side effects are considered rare, but there are several of them, some more serious than others. The oral drops are also known for having a particularly bitter taste, but that can be combated by refrigeration, which seems to dull the taste a bit.
  1. Common Side Effects

    • Vomiting and diarrhea are the most common side effects. While mild diarrhea isn't too serious, it is something that needs to be monitored. If the cat's diarrhea becomes very watery or it contains blood, stop giving it the clindamycin and contact your vet. Loss of appetite and weight loss, especially in conjunction with vomiting, are symptoms of a possible overdose. If your cat shows these symptoms while taking clindamycin, contact your vet and discontinue use.

    Allergic Reactions

    • If your cat is allergic to lincomycin, a related antibiotic, clindamycin could cause a similar allergic reaction. Symptoms of an allergic reaction include swelling, rashes or hives. Pale gums may also occur, however that might be a sign of dehydration caused by diarrhea. In either case, you should contact your vet. The most serious sign of an allergic reaction is seizure and you should contact your vet immediately should seizures occur.

    Liver and Kidneys

    • Animals with kidney or liver disease should not use clindamycin. If no other option is available, regular blood tests should be given. Even animals without liver or kidney disease should be tested on a regular basis if the cat takes the medication for longer than a month. These tests are needed to make certain that the drug is clearing the cat's system and to prevent an overdose.

    Pregnant and Nursing Cats

    • Clindamycin is capable of passing through the placenta in pregnant cats, and through the milk of nursing cats. The most common side effect is diarrhea in nursing kittens, but make sure to inform your vet if your cat is pregnant or nursing. If the kittens were premature or have other conditions, your vet may decide to use a different antibiotic.

    Drug Interactions

    • Clindamycin becomes less effective when used in combination with erythromycin, another antibiotic. It should be used cautiously if the cat is on neuromuscular blockers, which are normally administered by veterinarians before operations. Make sure your vet knows about all the medications you are giving, or have recently given, your cat.