Polycystic Kidney Disease in Persian Cats

Although found in several breeds of cat, polycystic kidney disease (PKD) is most prevalent among Persian and Persian-cross cats. It is characterized by kidneys riddled with fluid-filled cysts that grow progressively larger, destroying kidney tissue and disrupting normal function.

  1. Features

    • PKD is, according to Pet Education, an autosomal dominant inherited disease, which means that Persian kittens need only inherit one gene to develop the illness.

    Signs &Symptoms

    • Watch for signs of kidney failure.

      PKD typically presents as kidney failure in Persian cats between 3 and 10 years of age. Symptoms include weakness, weight loss, loss of appetite, excess thirst and urination, vomiting, diarrhea, seizures and blindness.

    Diagnosis

    • Kidney failure is diagnosed through a urinalysis and complete blood panel. However, to determine that kidney failure is due to PKD, says Le Bordo Persians, a veterinarian must perform an ultrasound to confirm the presence of cysts.

    Treatment

    • A veterinarian will prescribe a strict regimen for a PKD cat.

      PKD cysts cannot be surgically removed. A Persian's kidney failure must be treated and managed with corrective fluids, medications, diet, hormones and supplements.

    Prognosis

    • With proper veterinary management and diligent owner care, Persian cats with PKD can live relatively normal lives. In fact, says Le Bordo Persians, "most PKD cats actually die from something other than renal failure due to PKD."

    Prevention/Solution

    • With careful management, a PKD Persian can have a long life.

      PKD is inherited, so prevention is not an option. Steps can be taken to control a Persian's health by having an exploratory ultrasound to check for signs of PKD. If cysts are present, the owner and veterinarian can begin managing the cat's condition immediately.