Ivermectin Toxicity in Cats

Ivermectin is an anti-parasitic drug that causes neurological damage to parasites such as fleas and worms. It is used to prevent and treat parasitic infestations in horses, dogs and cats.

  1. Identification

    • Ivermectin toxicity is a phrase used to describe harmful effects if too much of the drug is administered.

    Dose

    • According to the book "Applied Pharmacology for Veterinary Technicians," toxicity occurred in laboratory tests when ivermectin was administered at 20 to 30 times the recommended therapeutic dose. Toxicity occurs more readily in dogs than cats.

    Effects

    • Symptoms of an ivermectin overdose include depression, lethargy, excessive salivation, dilated pupils, vomiting, shaking, disorientation, muscle weakness, ataxia, blindness, depressed heart rate, refusal to eat, slow respiratory rate, an inability to rise, inability to respond to stimuli, seizures, coma or death.

    Time Frame

    • Acute symptoms of ivermectin toxicity occur 4 to 12 hours after administration. Further symptoms may be noticed 48 to 96 hours later.

    Warning

    • If you suspect your cat is experiencing adverse effects related to ivermectin toxicity, speak to an emergency veterinary medical care provider immediately.