What color will the kittens be if female is a calico and male cream?

Here's how to figure out the possible kitten colors:

* Calico Cats: Calico cats are female and get their distinctive color pattern from a combination of the X chromosome and a gene called the "orange gene." Females have two X chromosomes, one from each parent. The orange gene is located on the X chromosome. So, a calico cat has one X chromosome with the orange gene and one X chromosome without it.

* Cream Cats: Cream cats are typically male and usually get their color from a recessive gene.

Here's how it works out:

* The female cat (calico) will pass on either an X chromosome with the orange gene (orange) or an X chromosome without the orange gene (non-orange).

* The male cat (cream) will pass on a Y chromosome.

Possible Combinations:

* Orange X + Y = Orange Male Kitten

* Non-Orange X + Y = Non-Orange Male Kitten

Therefore, the kittens could be either orange or non-orange. They will not be calico because they will inherit only one X chromosome from their mother.

Important Notes:

* The color of the non-orange kittens can vary. They could be white, black, tabby, or a combination of these colors.

* The exact shade of orange can also vary.

* There is a small chance a male calico could exist, but this is extremely rare. It happens due to a genetic anomaly.

Let me know if you have any other questions!