Here's what's important to remember:
* Calico is a coat pattern, not a breed: Calico cats can be any breed of cat with a calico coat.
* Litter size varies: The average litter size for domestic cats is around 4-6 kittens, but it can range from 1 to 10 or more.
So, a calico cat could have anywhere from 1 to 10 or more kittens, just like any other cat.