Can Prednisone Cause Diabetes in Dogs?

Prednisone can be a helpful medication in managing a wide range of illnesses and diseases in dogs. However, even short-term use may cause side effects. Long-term use may increase the risk of diabetes in a dog. However, the benefits of prednisone may outweigh the risks.

  1. Understanding Prednisone

    • Prednisone is a common medication in the class of drugs known as corticosteroids. Prednisone is a synthetic corticosteroid that is converted into prednisolone in the liver. Prednisolone aids in treating autoimmune conditions and inflammation in dogs, from relatively minor allergies to more serious conditions such as inflammatory bowel disease.

    Side Effect: Diabetes

    • While considered a generally safe drug, prednisone can cause significant side effects. One possible risk of long-term use is diabetes. According to veterinarian Dr. Mike Richards, it is "widely accepted that prednisone may predispose dogs and cats to diabetes." Prednisone may cause insulin resistance, leading to diabetes. Prednisone may also complicate management of diabetes, since the drug can affect blood sugar levels.

    Weighing Benefits and Risks

    • While prednisone may increase the risk of diabetes in dogs, the benefits of the drug's use may outweigh that risk. Some conditions that prednisone treats can be life-threatening or greatly decrease a dog's quality of life. Diabetes, while serious and potentially fatal if left untreated, can often be successfully managed through exercise, diet and insulin. As a dog owner, you should discuss the potential benefits and risks of using prednisone with your veterinarian.