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Cortisol
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A dog's body needs cortisol to create glucose, conserve it and to perform anti-inflammatory functions. A dog with a cortisol deficiency could experience vomiting, tiredness and weight loss.
Hydrocortisone
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Hydrocortisone can be given intravenously to a dog experiencing a critical drop in cortisol levels. A dog with Addison's disease can be giving hydrocortisone tablets to control the condition, according to "The Whole Dog Journal."
Considerations
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It can take time to determine the correct dosage of hydrocortisone needed to compensate for a dog's cortisol deficiency, so the amount administered could be raised or lowered until the right balance is found.
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Hydrocortisone for Cortisol Deficiency
Addison's disease is a fairly rare endocrine disorder in dogs. It causes an lack of production of cortisol, which can result in a dog requiring hydrocortisone.