Side Effects of Buprenex in a Canine

Buprenorphine, also known as Buprenex, is a narcotic pain medication stronger than morphine but which produces fewer negative gastrointestinal side effects than morphine. Buprenex is formulated for humans but, with approval and a prescription from a veterinarian, can be used in dogs and cats. Stop using Buprenex and contact your veterinarian immediately if your dog experiences negative side effects due to the drug.

  1. Allergic Reactions

    • Buprenex may cause allergies in some dogs. Look for signs that your dog is having trouble breathing, stops eating, or has skin irritation after taking Buprenex. Your dog may require a different dosage or she may not be able to use Buprenex at all.

    Disease Complications

    • Buprenex is metabolized by the liver for use in the body. Dogs with liver disease are unable to properly metabolize the medication. Using Buprenex may complicate the disease and produce worse symptoms. Buprenex may also worsen symptoms of kidney disease, Addison's disease and thyroid disease. The drug may speed the heart rate, so it is unsafe for dogs with heart disease.

    Drug Interactions

    • Buprenex, like other medications, is unsafe for dogs when combined with certain other medications. If your dog is currently taking antihistamines or tranquilizers, for example, taking Buprenex may cause deadly reactions.

    Sedative Effects

    • Buprenex is a powerful drug that may cause your dog to feel drowsy. She may act tired, groggy, or slightly disoriented, and she may sleep more than usual.