Side Effects of Phenylpropanol for Dogs

Phenylpropanol (also known as phenylpropanolamine) is a drug that is commonly prescribed by veterinarians to treat urinary incontinence in dogs. Urinary incontinence is a condition in which urine leaks from the bladder. Phenylpropanol works by increasing the tone of the urethra (the tube that carries urine from the bladder). Phenylpropanol is considered safe; however, there have been some side effects associated with its use.

  1. Allergic Reaction

    • Phenylpropanol may cause an allergic reaction in dogs that have a hypersensitivity to the drug. The symptoms of an allergic reaction are swelling of the lips, eyes or tongue; hives; and difficulty breathing. This is a life-threatening condition that may require emergency medical treatment.

    Drug Interactions

    • Phenylpropanol may interact with other medications. To avoid this scenario, be certain to tell your veterinarian of any other medications your dog is taking. Some medications that may cause adverse effects if taken with phenylpropanol are ephedrine, aspirin and tricyclic antidepressants.

    General Side Effects

    • Phenylpropanol may cause restlessness, loss of appetite and high blood pressure in dogs. This medication should be used with caution in dogs that suffer from pre-existing conditions such as high blood pressure, glaucoma, overactive thyroid, diabetes or heart disease.