What Are the Causes of Elevated Liver Enzymes in Dogs?

The dog liver is an important component in metabolizing fats, proteins and carbohydrates. Without proper liver function, a dog's body cannot detoxify the body from metabolic waste. Elevated liver enzymes suggest a serious health issue in dogs and should be dealt with under veterinarian care.

  1. Jaundice

    • If the liver is unable to remove bilirubin, a waste product from the break down of hemoglobin, it will accumulate and is toxic. Bilirubin is responsible for the yellow color of jaundice around the whites of the eyes or the pale areas of the gums.

    Pancreatitis

    • Gamma glutamyltransferase (GGT) is mostly concentrated in the kidneys and pancreas. Elevated levels of GGT in the liver suggest new secretions as a result of pancreatitis or an obstruction in the bile duct.

    Cushings Disease

    • Cushings disease causes a production of excessive levels of adrenal hormones, particularly corticosteroids. The result is an increase in alkaline phosphatase in the liver as it attempts to rebalance salt levels.

    Infectious Hepatitis

    • Infectious herpes is transferred from dogs via contact or ingestion. With herpes, parasites can attack the liver and raise liver enzymes in an attempt to remove the assailants.

    Prevention: Dietary Management

    • Limit sodium intake as well as other foods, such as meat, that can overtax the liver's metabolism. This will prevent high levels of ammonia during digestion. Feed your dog carbohydrates and essential fatty acids.