The Side Effects of Keflex in Dogs

Keflex is the registered brand name for the drug Cephalexin, which works much like penicillin. Unlike penicillin, however, its effectiveness is much wider on bacteria. This antibiotic has been approved for use in humans by the FDA but has not yet been approved for use in animals. Veterinarians still prescribe it as it a very effective way to combat bacterial infections in dogs. Like most other drugs, Cephalexin can cause side effects.

  1. Vomiting

    • A mild side effect to Keflex is vomiting, which is usually not an emergency and can be easily remedied. If the dog is vomiting excessively then a trip to the veterinarian may be needed but usually dogs who throw up after taking Keflex do so because the drug has a harsh reaction to an empty stomach. Giving Keflex right after a meal generally prevents vomiting.

    Diarrhea

    • Although it is not a common Keflex side effect, having loose stool or diarrhea is a possibility while on this course of antibiotics. Veterinarians are not overly worried with a dog that has diarrhea while on Keflex, as the dog's digestive tract tends to settle down once it is used to having cephalexin in its system. If the diarrhea does continue then dehydration can become a concern. The veterinarian may change antibiotics if this side effect does not clear up or it is too much for the owner to handle.

    Appetite Loss

    • Certain dogs that go on a course of Keflex lose their appetite, which increases the chance of vomiting after taking the drug. This particular problem can be fixed by adding gravy or chicken stock to the dog's food. Most dogs won't be able to resist a treat like this. If this still does not work, the veterinarian may switch antibiotics or prescribe an appetite stimulant.

    Allergic Reaction

    • Dogs with hypersensitivity to penicillin and similar drugs can have allergic reactions when given Keflex. If a reaction is suspected, contact a veterinarian immediately. If the allergic reaction is severe enough it can be fatal. Monitoring a dog after giving it any drug is essential so you can respond as fast as possible if any symptoms of an allergic reaction do occur. If after giving Keflex your dog begins to develop hives or a rash on its body or begins scratching excessively, he may be having an allergic reaction. Swelling of the face or body parts or rapid and shallow breathing may be more serious signs of a reaction to the drug and the dog should see a veterinarian as soon as possible.