Clavamox Reactions in Dogs

Clavamox (amoxicillin trihydrate/clavulanate potassium) is a broad-spectrum antibiotic in the penicillin family. Your veterinarian may prescribe it for any number of infections, including but not limited to abscesses, dental infections, respiratory infections, urinary infections and infected wounds. With a veterinarian's support, Clavamox is generally safe to use, with just a few words of caution.

  1. Allergic reactions

    • Just as some people are allergic to penicillin, so some dogs may be susceptible to allergic reactions from Clavamox and other antibiotics in the penicillin family. Signs of an allergic reaction include difficulty breathing, swelling around the face or limbs, loss of coordination, rash, fever and irregular heartbeat. If you think your dog may be having an allergic reaction--and this can happen very quickly--contact your veterinarian immediately. An allergic reaction can be a life-or-death emergency. There is no way to know if your dog will be allergic to penicillin until you administer the medication.

    Adverse reactions

    • Some dogs experience gastric upset from Clavamox. Symptoms include diarrhea, vomiting and loss of appetite. Tell your veterinarian if your dog develops any gastric symptoms. Your veterinarian may recommend that you give the medicine with or without food, depending on your dog's particular response to the drug. In some cases, your veterinarian may instruct you to discontinue Clavamox and try something else.

    Unexpected reactions

    • As with any medicine, your dog may have an unexpected reaction, if the medication simply does not agree with his system. Monitor your dog closely while he is on any medication. If you notice anything unusual, talk to your veterinarian. There may be another medication that will work just as well on the infection without any unpleasant effects for your dog.

    Other medications

    • The following drugs may interact with Clavamox: aminoglycosides, anti-inflammatory drugs, blood thinners, cephalosporins, chloramphenicol, dipyradamole, erythromycin, pain killers, pentoxifyline, probenecid, sulfinpyrazone, and tetracycline. Always tell your veterinarian about any other medications your dog is taking, including supplements.

    Contraindications/Cautions

    • Tell your veterinarian if your dog has a known history of allergy to penicillins or cephalosporins. Your veterinarian may be able to prescribe a different antibiotic that is not related to penicillin or cephalosporin. Also, if you are allergic to penicillin, be very careful handling your dog's Clavamox.