Potassium Bromide for Canine Epilepsy

Canine epilepsy is a seizure condition caused by a miscommunication of the electrical impulses in the brain, which triggers uncontrollable movement of the muscles of the dog's body. Most cases of canine epilepsy are treated by one or more oral medications. Potassium bromide is one of these medications.

  1. Potassium Bromide

    • Potassium bromide is used to treat canine epilepsy.

      Potassium bromide (KBr) can be used alone or in conjunction with phenobarbital. Unlike phenobarbital, which can cause liver problems, KBr is stored in body fluids and is eliminated by the kidneys.

    Side Effects

    • During the initial weeks of taking potassium bromide, side effects can occur, and may include excessive hunger, thirst and urination as well as lethargy and ataxia (loss of coordination).

    Toxicity

    • Bromide toxicity is uncommon, however dogs with renal insufficiency or those on a very high dose may experience severe ataxia, sedation or stupor, or muscle spasms.

    Mode Of Administration

    • KBr is available in liquid or capsule form. KBr remains in the dog's body for a long period of time, up to 24 days, which allows for more flexibility in dosing schedules, though twice daily dosing is recommended.

    Dosage

    • A loading dose (large initial dose) is recommended because KBr can take up to four months before it begins to work. There is a complex formula that your veterinarian will use to determine both the loading dose, given for the first five days, and the daily dose given each day thereafter.