Some medications are not indicated in use for animals with certain health problems. It may be that the medications themselves could be harmful, or that the medication would open up the dog to further problems.
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Significance
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Dogs who are immune compromised are at a greater risk of secondary infection from flea bites. Dogs who suffer from autoimmune disorders may also process more of the medication itself, causing acute toxicity.
Indications
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Frontline brand flea and tick repellent is not indicated for use in autoimmune, pregnant or nursing dogs.
Effects
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Exposing an immune compromised dog to flea control products is dangerous. Serious side effects may occur, including but not limited to seizures and death. Speak to a licensed veterinary professional for advice when trying to control fleas on a dog with an autoimmune disease.
Warning
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The main ingredients in Frontline are the chemicals fipronil and methoprene. Methoprene is an insect growth regulator and fipronil is a poison. While the dose of poison is not harmful to a healthy dog, those who are immune compromised are more apt to suffer ill effects from use.
Speculation
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According to a 2002 study conducted by Murray State University, flea control products may be linked to the formation of autoimmune diseases. No conclusive evidence supports this, but cases have been observed that suggest a link between treatments and the development of the disease.
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