Lomustine, also known as CCNU, is used to treat resistant lymphoma and mast cell tumors in dogs. While this drug is potentially lifesaving while your dog is undergoing chemotherapy, there are possible side effects you should be aware of.
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Purpose
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CCNU is given to dogs while they are undergoing chemotherapy. It is administered by the owner as instructed by a veterinarian for 48 hours after treatment.
Benefits
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CCNU may help reduce the size of mast cell tumors in dogs. Its greatest benefit is that it is given orally at home by the owner, reducing the number of trips to the veterinarian.
Potential Side Effects
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Potential side effects for dogs taking CCNU include vomiting, diarrhea, loss of appetite, low white blood cell count, low platelet count and liver toxicity. Some of these side effects, such as liver toxicity, occur very rarely.
Precautions
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Because some of the side effects associated with CCNU are very serious and could result in death, it is very important that you monitor your dog constantly during the 48 hours after treatment. Do not allow your dog to wander off and be sure you are aware of his location and condition at all times.
Warning
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If your dog begins showing a negative reaction to the CCNU treatment and is exhibiting signs of side effects, take him to the veterinarian right away. While some side effects such as diarrhea and loss of appetite may not seem severe, they could potentially lead to a very serious condition in your dog.
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