Veterinarians generally prescribe prednisone at a dose of 0.25 to 1 mg per pound of body weight, given once or twice a day. For example, a 10 lb dog might receive 2 to 5 mg of prednisone once a day, while a 50 lb dog might receive 12.5 to 25 mg of prednisone once or twice a day.
The duration of treatment with prednisone will also vary depending on the condition being treated and the individual dog's response to the medication. In some cases, short-term treatment of just a few days may be sufficient, while in other cases, long-term treatment may be necessary.
It is important to follow your veterinarian's dosing instructions carefully and to give your dog the medication exactly as prescribed. Do not adjust the dose or frequency of administration without first consulting your veterinarian, as prednisone can have significant side effects, especially if used incorrectly.