1. Toxicity: Foxglove contains cardiac glycosides, which are powerful substances that can affect the heart. Ingestion of any part of the foxglove plant can cause serious health problems, including irregular heartbeat, nausea, vomiting, diarrhea, and dizziness. In severe cases, foxglove poisoning can lead to heart failure and death.
2. Contraindications: Foxglove should not be used by people with certain heart conditions, such as heart block, atrial fibrillation, and Wolff-Parkinson-White syndrome. It should also be avoided by people with kidney disease, liver disease, or a history of allergies to foxglove or related plants.
3. Drug interactions: Foxglove can interact with a variety of medications, including digoxin, quinidine, verapamil, and diuretics. These interactions can increase the risk of side effects and toxicity.
4. Pregnancy and breastfeeding: Foxglove is not recommended for use during pregnancy or breastfeeding, as it can cross the placenta and enter breast milk.
5. Children: Foxglove should not be given to children, as they are more sensitive to its toxic effects.
It is important to use foxglove only under the supervision of a qualified healthcare professional. Foxglove should be used in the lowest effective dose for the shortest possible duration to minimize the risk of side effects and toxicity.