Some common examples of antipyretics include aspirin, ibuprofen, and acetaminophen. These drugs are available in a variety of formulations, including oral tablets, capsules, and liquids. Antipyretics are also available as topical gels, creams, and sprays.
Antipyretics are generally well-tolerated and have a low risk of side effects. However, some antipyretics, such as aspirin and ibuprofen, can cause gastrointestinal upset and bleeding. Acetaminophen can cause liver damage if it is taken in high doses or for a long period of time.
Antipyretics are used to treat fever in a variety of conditions, including the common cold, flu, and other infections. They are also used to treat fever caused by cancer and other medical conditions.
When using an antipyretic, it is important to follow the directions on the drug label. Do not take more than the recommended dose, and do not take the drug for longer than the recommended period of time. If you experience any side effects, stop taking the drug and talk to your doctor.
Side effects of antipyretics
The most common antipyretic drugs are salicylates, acetaminophen, and non-steroidal anti-inflammatory drugs (NSAIDs)
Salicylates, aspirin can cause gastrointestinal (GI) effects, such as heartburn, nausea and vomiting, gastrointestinal bleeding. Other adverse effectes include platelet dysfunction, bone marrow suppression, hypersensitivity reactions, tinnitus and hepatotoxicity.
Acetaminophen is relatively non-toxic; serious side effects include hepatic and renal toxicity. Overdose of paracetamol can cause potentially fatal liver damage. Hypersensitivity reactions occur rarely. There is weak anti-inflammatory and antiplatelet activity.
Nonsteroidal anti-inflammatory drugs (NSAIDs) may cause:
- Renal impairment
- Gl ulceration and bleeding
- Headache (less than acetylsalicylate)
- Tinnitus
- Hypersensitivity reactions
- Bronchospasm (acetylsalicylate)
- Platelet dysfunction (acetylsalicylate)