Here are some key aspects of lavender top (EDTA) tubes:
Anticoagulant: Lavender top tubes contain EDTA (ethylenediaminetetraacetic acid), an anticoagulant that chelates calcium and prevents blood from clotting. EDTA binds to calcium ions, essential for the activation of the coagulation cascade, thus effectively inhibiting the clotting process.
CBC and Blood Cell Analysis: Lavender top tubes are primarily used for complete blood count (CBC) and blood cell differential analysis. CBC provides information about the concentration and characteristics of various blood cells, including red blood cells (RBCs), white blood cells (WBCs), and platelets. Blood cell differential analysis involves examining the different types of white blood cells, such as neutrophils, lymphocytes, monocytes, eosinophils, and basophils.
Cell Morphology Preservation: EDTA preserves the morphology and integrity of blood cells, making them suitable for microscopic examination. This allows accurate identification and classification of different white blood cell types and the detection of any abnormalities in cell shape or size.
Sample Stability: Lavender top tubes with EDTA provide good sample stability for hematology analysis. Blood samples collected in EDTA tubes can be stored and transported at room temperature for several hours without significant changes in cell morphology or characteristics. However, it's crucial to consult laboratory guidelines for specific storage and handling requirements to ensure optimal sample quality.
Additional Parameters: Depending on the laboratory, specialized tests may be performed on samples collected in lavender top (EDTA) tubes. These tests could include hemoglobin A1c (HbA1c) for monitoring glucose control in individuals with diabetes, reticulocyte count for assessing bone marrow activity, and certain coagulation studies, such as platelet function tests.
It's worth noting that lavender top (EDTA) tubes are used for hematology purposes and are not suitable for tests that require serum or plasma. For serum or plasma-based tests, other types of blood collection tubes are used, such as red top (clot activator) or serum separator tubes.