Can toy breed have large dog?

Toy breeds should not be bred with larger breeds. The size difference can cause health problems for both the mother and the puppies. Toy breed mothers may have difficulty carrying and giving birth to large puppies, and the puppies may be too big for the mother's milk supply. Additionally, the puppies may be more likely to develop joint problems and other health issues later in life.

If you are interested in breeding toy dogs, please consider finding a mate of a similar size and breed. This will help to ensure the health and safety of both the mother and the puppies.