If 2 dogs with the same parents come from different litters are they brother and sister?

Yes, if two dogs have the same parents but come from different litters, they are still considered brother and sister (or siblings).

Here's why:

* Litter: A litter refers to a group of puppies born to the same mother at the same time.

* Siblings: Siblings share the same parents, regardless of whether they were born in the same litter.

Therefore, even though the dogs were born in different litters, they share the same biological parents and are thus siblings.