What are the top three dogs that have most puppies in a litter?

It's impossible to definitively say which three dog breeds have the most puppies in a litter because:

* Breed variation: Litter sizes can vary greatly within the same breed due to individual dog factors like age, health, and genetics.

* Limited data: There isn't a comprehensive, global database tracking every dog breed's average litter size.

However, some breeds are generally known for having larger litters than others. Here are three contenders, with the caveat that these are averages and individual litters may vary:

1. Great Dane: These giants can have litters ranging from 6 to 12 puppies, with some exceeding that number.

2. English Bulldog: English Bulldogs are known for having larger litters, with an average of 6-8 puppies.

3. Mastiff: Another giant breed, Mastiffs can have litters of 8-12 puppies, sometimes even more.

Important note: While large litters are possible, it's crucial to remember that a healthy litter size is more important than a huge one. A smaller litter allows for better care and attention from the mother dog and increases the chances of all puppies thriving.