Once the cattle reached a railhead, such as Chicago, they would be loaded onto railroad cars and transported to their final destination. This method of transportation was more efficient and faster than walking the cattle the entire distance, and it also reduced the risk of losing or injuring animals during the journey.
In addition to cattle drives and rail transport, some cattle were also transported by steamboat up the Missouri River to markets in Kansas City or Omaha, where they could be loaded onto trains for the rest of the journey to Chicago.