Does Polymyxin B Sulfate burn when put in eye?

Polymyxin B sulfate ophthalmic solution is an antibiotic medication used to treat bacterial eye infections. It is typically applied topically to the affected eye(s) in the form of eye drops. Polymyxin B sulfate may cause a temporary stinging or burning sensation when first applied to the eye, but this usually resolves quickly. If you experience severe or persistent pain, redness, or swelling after using polymyxin B sulfate, you should stop using the medication and consult your doctor.