* Harpy eagles (_Harpia harpyja_) are large eagles that are found in tropical rainforests from Mexico to Argentina. They are one of the most powerful birds of prey in the world and are capable of taking down animals much larger than themselves, including the golden lion tamarin.
* Ocelots (_Leopardus pardalis_) are small, spotted cats that are found in tropical rainforests from Mexico to Argentina. They are opportunistic predators and will eat whatever they can find, including the golden lion tamarin.
* Jaguars (_Panthera onca_) are large, spotted cats that are found in tropical rainforests from Mexico to Argentina. They are the most powerful predators in the Americas and are capable of taking down animals much larger than themselves, including the golden lion tamarin.
* Boa constrictors (_Boa constrictor_) are large snakes that are found in tropical rainforests from Mexico to Argentina. They are ambush predators and will wait for their prey to come close before striking and wrapping around it. The golden lion tamarin is a common prey item for boa constrictors.
* Humans (_Homo sapiens_) are the biggest threat to the golden lion tamarin. They hunt them for their fur, meat, and as pets. The destruction of their habitat is also a major threat to the golden lion tamarin.