- Cooper's hawks
- Sharp-shinned hawks
- Great horned owls
- Northern goshawks
- Red-tailed hawks
- Bald eagles
- Golden eagles
- Prairie falcons
- Peregrine falcons
- Merlins
- Northern shrikes
- Loggerhead shrikes
In addition to these natural predators, the American kestrel is also vulnerable to human-related threats, such as habitat loss, pollution, and hunting.