- Other raptors: Peregrine falcons may compete with other raptors, such as eagles and hawks, for food and territory. These raptors may also attack peregrine falcons or their nests.
- Large birds: Large birds, such as ravens and crows, may also prey on peregrine falcons or their eggs.
- Mammals: Mammals, such as foxes, coyotes, and raccoons, may raid peregrine falcon nests and eat the eggs or young chicks.
- Humans: Humans are the biggest threat to peregrine falcons. Habitat destruction, hunting, and pollution have all contributed to the decline of peregrine falcon populations in the past.