- Other fish, such as larger species of fish including bass, trout, and pike
- Amphibians such as frogs and newts
- Aquatic insects such as dragonfly nymphs and water beetles
- Reptiles, including snakes and lizards
- Some types of birds such as herons and kingfishers
- Even other guppies, as they are cannibalistic, meaning they may prey on younger or smaller guppies
Guppies are a common food source and prey item for many other animals as they are abundant, small, relatively slow-moving and live in a variety of water bodies from streams and rivers to ponds and lakes