2. Warm them up. Baby mice are very sensitive to cold, so if their mother is not nursing them, they may need to be warmed up. You can do this by placing them in a warm, dark place, such as a box lined with a soft cloth. You can also use a heating pad set on low, being sure to place a barrier, like a towel, between the heating pad and the babies to prevent direct heat.
3. Feed them. If the mother mouse is not nursing her babies, you may need to feed them yourself. You can use a commercial kitten milk replacer or make your own by mixing one part heavy cream with two parts water. Feed the babies every 2-3 hours, using a small syringe or bottle.
4. Handle them. Baby mice need to be handled regularly to help them socialize and become accustomed to human contact. Try to handle them for a few minutes each day, being gentle and avoiding sudden movements.
5. Reunite them with their mother. If the mother mouse does not reject her babies after a few hours or a day, you can try to reunite them. Place the babies in a nest with the mother and observe her behavior. If she accepts them, you can leave them together. If she rejects them again, you may need to continue to care for them yourself.
6. Seek veterinary care. If you are unable to care for the baby mice yourself or if they appear sick, take them to a veterinarian.