What is fentocin?

Fentocin (also known as carbetocin) is a synthetic peptide analogue of oxytocin. It is a potent and long-acting uterotonic agent that is used primarily to prevent and treat postpartum hemorrhage. Fentocin works by stimulating the contraction of the uterine muscles, thereby reducing the risk of excessive bleeding after childbirth. It also has some other uses, such as induction of labor and induction of abortion.

Fentocin is a synthetic octapeptide that is derived from oxytocin, the natural hormone produced by the hypothalamus and released by the pituitary gland. However, fentocin has a longer half-life and greater potency than oxytocin, which makes it better suited for certain clinical applications.

Fentocin is typically administered intravenously or intramuscularly. The dosage and frequency of administration depend on the specific indication for use. In most cases, the starting dose is 100 micrograms given by slow intravenous injection. This dose may be repeated every 4 to 6 hours as needed.

Fentocin is generally well-tolerated. The most common side effects include nausea, vomiting, headache, and hypotension. Serious side effects, such as seizures and cardiac arrhythmias, are rare but can occur.

Fentocin is contraindicated in patients with eclampsia, pre-eclampsia, or any other condition that is characterized by severe hypertension. It should also be used with caution in patients with heart disease, liver or kidney disease, or a history of seizures.

Fentocin is a safe and effective medication for the prevention and treatment of postpartum hemorrhage. It is also useful for other obstetrical indications, such as induction of labor and induction of abortion. However, it should be used only under the supervision of a qualified healthcare professional.